Asp provides a simple solution to the problem of obtaining a quantitative measure of the similarity between two molecules. Similarity indices give a quantitative measure of the concept of bioisosterism and help guide researchers in deciding which compounds should be synthesized and submitted for biological screening.
Ron George
Executive Vice President Oxford Molecular, Inc. 7005 Backlick Court Suite 200 Springfield, VA 22151 USA 703-658-4854 fax:703-658-4887